The database of various piRNA associated data to support piRNA functional study

piRBase is a manually curated resource of piRNAs, which focused on piRNA function analyses as well as piRNA annotation.

piRBase provides the following information and tools to facilitate piRNA function analyses:
1: The number of piRNA sequences has reached 173 million, from 264 datasets in 21 organisms.
2: piRBase classifies piRNAs by biogenesis according to genomic annotation.
3: Regulatory piRNAs and their mRNA targets are extracted from the literature. Predicted piRNA target lncRNAs are also added to the present release.
4: piRBase combines DNA methylation data and H3K9me3 data to facilitate studies of piRNA function in epigenetic regulation.
5: 8 types of cancers (Breast, Bladder, Pancreas, Gastric, Liver, Kidney, Myeloma & Colorectal cancer) related piRNAs are included.
6: Genome Browser provides improved integration and visualization of the relations between piRNA data and other related information.


> Aug 2018: piRBase release v2.0
>> Online tools are added
>> The information of cancer related piRNAs is added
>> New piRNA targets are added
>> New piRNA records are added

> Nov 2014: piRBase release v1.0

Please cite the following article in addition to the primary data sources:
piRBase: a web resource assisting piRNA functional study.
Database 2014; doi: 10.1093/database/bau110

Any questions or suggestions please contact: Shunmin He heshunmin@gmail.com.

This is open data distributed under the terms of the Creative Commons Attribution Non-Commercial License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. If you are a commercial user, please contact us.