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RefSeq Gene
 

RefSeq Gene MOG

RefSeq: NM_002433.4   Status: Reviewed
CDS: 3' complete
OMIM: 159465
Entrez Gene: 4340
PubMed on Gene: MOG
PubMed on Product: myelin-oligodendrocyte glycoprotein isoform beta1 precursor
GeneCards: MOG
AceView: MOG
Stanford SOURCE: NM_002433

Summary of MOG

The product of this gene is a membrane protein expressed on the oligodendrocyte cell surface and the outermost surface of myelin sheaths. Due to this localization, it is a primary target antigen involved in immune-mediated demyelination. This protein may be involved in completion and maintenance of the myelin sheath and in cell-cell communication. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].


mRNA/Genomic Alignments

The alignment you clicked on is first in the table below.
BROWSER | SIZE IDENTITY CHROMOSOME  STRAND    START     END              QUERY      START  END  TOTAL
-----------------------------------------------------------------------------------------------------
browser |  1910   99.9%  6_ssto_hap7     +    965314    980702             NM_002433     1  1910  1920
browser |  1910  100.0%          6     +  29624758  29640149             NM_002433     1  1910  1920
browser |  1910   99.9%  6_apd_hap1     +    928284    943674             NM_002433     1  1910  1920
browser |  1910   99.9%  6_cox_hap2     +   1143559   1158951             NM_002433     1  1910  1920
browser |  1910   99.7%  6_dbb_hap3     +    928111    943503             NM_002433     1  1910  1920
browser |  1910   99.8%  6_mann_hap4     +    927718    943106             NM_002433     1  1910  1920
browser |  1906   99.8%  6_mcf_hap5     +    927947    943331             NM_002433     1  1910  1920
browser |  1910   99.7%  6_qbl_hap6     +    928077    943469             NM_002433     1  1910  1920

Position: chr6_ssto_hap7:965314-980702
Genomic Size: 15389
Strand: +
Gene Symbol: MOG
CDS Start: complete
CDS End: complete

Position: chr6_mcf_hap5:927947-943331
Genomic Size: 15385
Strand: +
Gene Symbol: MOG
CDS Start: complete
CDS End: complete

Position: chr6_qbl_hap6:928077-943469
Genomic Size: 15393
Strand: +
Gene Symbol: MOG
CDS Start: complete
CDS End: complete

Position: chr6:29624758-29640149
Band: 6p22.1
Genomic Size: 15392
Strand: +
Gene Symbol: MOG
CDS Start: complete
CDS End: complete

Position: chr6_apd_hap1:928284-943674
Genomic Size: 15391
Strand: +
Gene Symbol: MOG
CDS Start: complete
CDS End: complete

Position: chr6_cox_hap2:1143559-1158951
Genomic Size: 15393
Strand: +
Gene Symbol: MOG
CDS Start: complete
CDS End: complete

Position: chr6_dbb_hap3:928111-943503
Genomic Size: 15393
Strand: +
Gene Symbol: MOG
CDS Start: complete
CDS End: complete

Position: chr6_mann_hap4:927718-943106
Genomic Size: 15389
Strand: +
Gene Symbol: MOG
CDS Start: complete
CDS End: complete

Links to sequence:

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Data last updated: 2013-05-15

Description

The RefSeq Genes track shows known human protein-coding and non-protein-coding genes taken from the NCBI RNA reference sequences collection (RefSeq). The data underlying this track are updated daily.

Display Conventions and Configuration

This track follows the display conventions for gene prediction tracks. The color shading indicates the level of review the RefSeq record has undergone: predicted (light), provisional (medium), reviewed (dark).

The item labels and display colors of features within this track can be configured through the controls at the top of the track description page. This page is accessed via the small button to the left of the track's graphical display or through the link on the track's control menu.

  • Label: By default, items are labeled by gene name. Click the appropriate Label option to display the accession name instead of the gene name, show both the gene and accession names, or turn off the label completely.
  • Codon coloring: This track contains an optional codon coloring feature that allows users to quickly validate and compare gene predictions. To display codon colors, select the genomic codons option from the Color track by codons pull-down menu. For more information about this feature, go to the Coloring Gene Predictions and Annotations by Codon page.
  • Hide non-coding genes: By default, both the protein-coding and non-protein-coding genes are displayed. If you wish to see only the coding genes, click this box.

Methods

RefSeq RNAs were aligned against the human genome using blat; those with an alignment of less than 15% were discarded. When a single RNA aligned in multiple places, the alignment having the highest base identity was identified. Only alignments having a base identity level within 0.1% of the best and at least 96% base identity with the genomic sequence were kept.

Credits

This track was produced at UCSC from RNA sequence data generated by scientists worldwide and curated by the NCBI RefSeq project.

References

Kent WJ. BLAT - the BLAST-like alignment tool. Genome Res. 2002 Apr;12(4):656-64.

Pruitt KD, Tatusova T, Maglott DR. NCBI Reference Sequence (RefSeq): a curated non-redundant sequence database of genomes, transcripts and proteins. Nucleic Acids Res. 2005 Jan 1;33(Database issue):D501-4.