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RefSeq Gene
 

RefSeq Gene BAG6

RefSeq: NM_080703.2   Status: Reviewed
CDS: full length
OMIM: 142590
Entrez Gene: 7917
PubMed on Gene: BAG6
PubMed on Product: large proline-rich protein BAG6 isoform b
GeneCards: BAG6
AceView: BAG6
Stanford SOURCE: NM_080703

Summary of BAG6

This gene was first characterized as part of a cluster of genes located within the human major histocompatibility complex class III region. This gene encodes a nuclear protein that is cleaved by caspase 3 and is implicated in the control of apoptosis. In addition, the protein forms a complex with E1A binding protein p300 and is required for the acetylation of p53 in response to DNA damage. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].


mRNA/Genomic Alignments

The alignment you clicked on is first in the table below.
BROWSER | SIZE IDENTITY CHROMOSOME  STRAND    START     END              QUERY      START  END  TOTAL
-----------------------------------------------------------------------------------------------------
browser |  3798  100.0%          6     -  31606805  31620477             NM_080703     1  3798  3814
browser |  3798  100.0%  6_cox_hap2     -   3116416   3130096             NM_080703     1  3798  3814
browser |  3798  100.0%  6_dbb_hap3     -   2892376   2906056             NM_080703     1  3798  3814
browser |  3798  100.0%  6_mann_hap4     -   2949688   2963366             NM_080703     1  3798  3814
browser |  3798  100.0%  6_mcf_hap5     -   2986492   3000157             NM_080703     1  3798  3814
browser |  3798  100.0%  6_qbl_hap6     -   2900437   2914115             NM_080703     1  3798  3814
browser |  3798  100.0%  6_ssto_hap7     -   2937602   2951276             NM_080703     1  3798  3814

Position: chr6_mann_hap4:2949688-2963366
Genomic Size: 13679
Strand: -
Gene Symbol: BAG6
CDS Start: complete
CDS End: complete

Position: chr6_dbb_hap3:2892376-2906056
Genomic Size: 13681
Strand: -
Gene Symbol: BAG6
CDS Start: complete
CDS End: complete

Position: chr6_cox_hap2:3116416-3130096
Genomic Size: 13681
Strand: -
Gene Symbol: BAG6
CDS Start: complete
CDS End: complete

Position: chr6_ssto_hap7:2937602-2951276
Genomic Size: 13675
Strand: -
Gene Symbol: BAG6
CDS Start: complete
CDS End: complete

Position: chr6_mcf_hap5:2986492-3000157
Genomic Size: 13666
Strand: -
Gene Symbol: BAG6
CDS Start: complete
CDS End: complete

Position: chr6_qbl_hap6:2900437-2914115
Genomic Size: 13679
Strand: -
Gene Symbol: BAG6
CDS Start: complete
CDS End: complete

Position: chr6:31606805-31620477
Band: 6p21.33
Genomic Size: 13673
Strand: -
Gene Symbol: BAG6
CDS Start: complete
CDS End: complete

Links to sequence:

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Data last updated: 2013-05-15

Description

The RefSeq Genes track shows known human protein-coding and non-protein-coding genes taken from the NCBI RNA reference sequences collection (RefSeq). The data underlying this track are updated daily.

Display Conventions and Configuration

This track follows the display conventions for gene prediction tracks. The color shading indicates the level of review the RefSeq record has undergone: predicted (light), provisional (medium), reviewed (dark).

The item labels and display colors of features within this track can be configured through the controls at the top of the track description page. This page is accessed via the small button to the left of the track's graphical display or through the link on the track's control menu.

  • Label: By default, items are labeled by gene name. Click the appropriate Label option to display the accession name instead of the gene name, show both the gene and accession names, or turn off the label completely.
  • Codon coloring: This track contains an optional codon coloring feature that allows users to quickly validate and compare gene predictions. To display codon colors, select the genomic codons option from the Color track by codons pull-down menu. For more information about this feature, go to the Coloring Gene Predictions and Annotations by Codon page.
  • Hide non-coding genes: By default, both the protein-coding and non-protein-coding genes are displayed. If you wish to see only the coding genes, click this box.

Methods

RefSeq RNAs were aligned against the human genome using blat; those with an alignment of less than 15% were discarded. When a single RNA aligned in multiple places, the alignment having the highest base identity was identified. Only alignments having a base identity level within 0.1% of the best and at least 96% base identity with the genomic sequence were kept.

Credits

This track was produced at UCSC from RNA sequence data generated by scientists worldwide and curated by the NCBI RefSeq project.

References

Kent WJ. BLAT - the BLAST-like alignment tool. Genome Res. 2002 Apr;12(4):656-64.

Pruitt KD, Tatusova T, Maglott DR. NCBI Reference Sequence (RefSeq): a curated non-redundant sequence database of genomes, transcripts and proteins. Nucleic Acids Res. 2005 Jan 1;33(Database issue):D501-4.